This probably is a horrible idea, but "interferring with mother nature" includes a lot of things we do as a matter of course: damming rivers to make lakes and dredging rivers to make them navigable being just two that sprang to mind. Arguably all of agriculture is "interferring with mother nature", as it building shelters of any sort to protect ourselves from the elements.
Screwing around with circadian rhythm is a real foul-up, though. Everything from mating cycles to crop ripening can be disturbed. We already do this with electric lights and other stuff for humans, especially in urban environments, and look how nuts they've become in the cities. Swarms of sleep deprived wackos, with or without meth.