Cannabis was touted for nerve pain. The evidence falls short

[Kamaji]

Cannabis was touted for nerve pain. The evidence falls short

A major review finds cannabis-based treatments fall short of delivering meaningful relief for chronic nerve pain.

Date:    January 19, 2026
Source:    Cochrane
Summary:
    Cannabis-based medicines have been widely promoted as a potential answer for people living with chronic nerve pain—but a major new review finds the evidence just isn’t there yet. After analyzing more than 20 clinical trials involving over 2,100 adults, researchers found no strong proof that cannabis products outperform placebos in relieving neuropathic pain. Even when small improvements were reported, especially with THC-CBD combinations, they weren’t large enough to make a real difference in daily life.

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Source:  https://www.sciencedaily.com/releases/2026/01/260118233547.htm

[mountaineer]

I keep waiting for evidence of mj's touted healing powers and have yet to see it.

[Smokin Joe]

I had friend in Colorado who suffered from shoulder pain, and basically made his living as a handyman. He bred a strain for CBD content, not THC, and claimed it helped without messing with his head.

I can't say for certain how much placebo effect was involved, and never tried any, but he claimed that helped. That pain may not have been nerve pain, per se, just older joints and cramped muscles, so the effect may not be the same for those suffering from something like fibromyalgia.

[PeteS in CA]

Surprise! Surprise! Surprise!

[Weird Tolkienish Figure]

It absolutely works for my body pains, but i hate it so there's that. Gives me anxiety and makes me dizzy.

Also chronic smokers wake up more during surgery.

[roamer_1]

It absolutely works for my body pains, but i hate it so there's that. Gives me anxiety and makes me dizzy.

Also chronic smokers wake up more during surgery.

I suffer from moderate neuropathy in my legs these days.
The only thing that seems to help is gabbapentin.

However, vit B seems to have good results too - not alone, but with the gabbapentin, 1 vit B complex, and my feet are just numb - which leads to blissful sleep.  Now, my body seems to get used to the vit b hit, and it will eventually quit having its effect. Then I have to get off from it for a while and do without. Maybe 3 weeks or so - then it works again.

I would really like something for that interim. Was fixin to try MJ edibles. The whole point is that I can't sleep due to neuropathic pain, and the reason I never used MJ all that much is because it knocks me right out. Two tokes and I am all gone. So that's a feature to me at this point.

[mountaineer]

I have a lot of joint pain (no pun intended) - osteoarthritis - and tried CBD. It did absolutely nothing, negative or positive. I tend to think many of the testimonials are placebo-related.

[Weird Tolkienish Figure]

I have a lot of joint pain (no pun intended) - osteoarthritis - and tried CBD. It did absolutely nothing, negative or positive. I tend to think many of the testimonials are placebo-related.

CBD will do nothing for some THC does work. For me it absolutely worked, but came with a bunch of other nasty things.

[roamer_1]

I have a lot of joint pain (no pun intended) - osteoarthritis - and tried CBD. It did absolutely nothing, negative or positive. I tend to think many of the testimonials are placebo-related.

Yeah. Same. I got my best effects from turmeric milk. CBD oil in its various forms did nothing.

BUT, is the whole show suspect, or just the CBD purveyors? That's why I may try edibles. There is also the whole setiva v. indica strains, which don't factor into CBD oil. In my case, I want to explore the indica strain because it helps with sleep, and relaxation.

Why isn't @corbe here advising? 

[Fishrrman]

"Reefer Madness"
Even back then, they knew what it was really all about...

[corbe]

   I take ES Tylenol and Burbon Whiskey for PAIN of any kind.  I toke my pipe, at night only, to temporarily escape the nonsense being shoved in my face on a daily basis.

[libertybele]

   I take ES Tylenol and Burbon Whiskey for PAIN of any kind. I toke my pipe, at night only, to temporarily escape the nonsense being shoved in my face on a daily basis.

You are fortunate...

[berdie]

I suffer from moderate neuropathy in my legs these days.
The only thing that seems to help is gabbapentin.

However, vit B seems to have good results too - not alone, but with the gabbapentin, 1 vit B complex, and my feet are just numb - which leads to blissful sleep.  Now, my body seems to get used to the vit b hit, and it will eventually quit having its effect. Then I have to get off from it for a while and do without. Maybe 3 weeks or so - then it works again.

I would really like something for that interim. Was fixin to try MJ edibles. The whole point is that I can't sleep due to neuropathic pain, and the reason I never used MJ all that much is because it knocks me right out. Two tokes and I am all gone. So that's a feature to me at this point.

[/b]



That's why I never liked it. But being able to sleep would be a benefit in today's world. I've never had to battle insomnia until the last year or so.

I take a b-complex and will have to look into that gabba stuff you mentioned.

[mountaineer]

Pain keeps me awake, and the CBD gummies didn't help me sleep at all. Ambien does, however, so I rely on one in every few days (not daily); yes, I'm aware that some people can't tolerate it and have had wacky side effects. Thankfully, I do not.
 

[corbe]

   A Trazadone (50 mg) at night goes a long way to help insure, for me, a Healthy Sleep. 

[roamer_1]

   A Trazadone (50 mg) at night goes a long way to help insure, for me, a Healthy Sleep.

A pipe on the porch before bed. That sounds like a blessing to me. Unless I tip over right there... Which weed can do to me. Falling asleep on the porch in subzero weather... Now that'll make you ache come morning... Or not. 

[Smokin Joe]

A pipe on the porch before bed. That sounds like a blessing to me. Unless I tip over right there... Which weed can do to me. Falling asleep on the porch in subzero weather... Now that'll make you ache come morning... Or not. 

Careful with that. I know one person who froze to death on her front step, and another who lost all his fingernails (kept the fingers, though) nodding off in his folks' back yard. A little yapper dog his folks had raised enough hell that it got let out into the fenced yard and jumped up on him and licked him in the face enough to wake him up, or he might have still been sitting there in the morning.

[PeteS in CA]

[roamer_1]

Careful with that. I know one person who froze to death on her front step, and another who lost all his fingernails (kept the fingers, though) nodding off in his folks' back yard. A little yapper dog his folks had raised enough hell that it got let out into the fenced yard and jumped up on him and licked him in the face enough to wake him up, or he might have still been sitting there in the morning.

Aw, I'd be alright.... or not... Without much in between 
I like to sit on the porch at night regardless of the weather - Well, not quite regardless - If it's blowin like a he-acaine, I'll skip the porch and hunker down. But mostly - And I mean way, way beyond where most folks would consider, I go out on the porch and sit in the sacred night, with a nice, hot cup of tea.

Yes, I will be there if it's -20 - My tea will be in my Klean Kanteen thermos jug instead of a mere camp cup, and I will be swaddled in my -40 bag, but yup even in that weather, I'll take my evening tea on the porch. It's a thing. The sacred night whispers to me. And I have to hear it.