Sleep deprivation increases brain protein linked to Alzheimer's disease

[rangerrebew]

Sleep deprivation increases brain protein linked to Alzheimer's disease


April 13, 2018

Losing just one night of sleep led to an immediate increase in beta-amyloid, a protein in the brain associated with Alzheimer's disease, according to a small, new study by researchers at the National Institutes of Health. In Alzheimer's disease, beta-amyloid proteins clump together to form amyloid plaques, a hallmark of the disease.

While acute sleep deprivation is known to elevate brain beta-amyloid levels in mice, less is known about the impact of sleep deprivation on beta-amyloid accumulation in the human brain. The study is among the first to demonstrate that sleep may play an important role in human beta-amyloid clearance.

https://www.news-medical.net/news/20180413/Sleep-deprivation-increases-brain-protein-linked-to-Alzheimers-disease.aspx

[WarmPotato]

I find myself getting TOO MUCH sleep!

[Gefn]

Bookmark  book 📖

[mountaineer]

I read about this several months ago. I've since been trying desperately to get enough sleep, considering my father had early-onset dementia of the Lewy body type.

[Polly Ticks]

I have five children.   This is REALLY bad news.

[thackney]

I read about this several months ago. I've since been trying desperately to get enough sleep, considering my father had early-onset dementia of the Lewy body type.

Staying awake at night worrying about not getting enough sleep?

[goodwithagun]

How much of this has to do with lifestyle? My mom, very sedentary, constantly complains about insomnia. She takes her phone everywhere, usually in her pocket. She didn’t know it tracked steps until I pointed it out to her. After a brief perusal I discovered she gets in about 1000 steps a day. No flames- I know there are those who take excellent care of themselves yet still have sleep problems. I’m just inquiring if there’s more to this.

[Polly Ticks]

On the other hand, Benjamin Franklin was reported to sleep for only 4 hours per night, and he seemed to do ok. 

[mirraflake]

Genetics mostly.

 My elderly aunt and her husband were health freaks even way back in the 60's and she got alzheimers.

A friends dad stared to get alzheimers in his late 50's and died from it age 66 and my friend who is now 59 is showing  begining signs of it and he has done everything he can-eat right, excercise, crossword puzzles-for years now.

Do a 23 and me genetic test to see if you have the varient for alzheimers gene. My wife and I don't nor parkinsons.

[mountaineer]

Staying awake at night worrying about not getting enough sleep?

Pretty much! 

[goodwithagun]

On the other hand, Benjamin Franklin was reported to sleep for only 4 hours per night, and he seemed to do ok.

I wonder if the decades of (the now debunked) low fat diet have an effect. I remember when my mom switched from whole to skim, and swapped out our Oreos for Snackwells. Ugh, and the yellow plastic squares somehow legally named low fat cheese singles