I haven't received a vaccine since I was a kid and got the measles shot. In all these years, I have not gotten the flu, pneumonia or anything else against which a vaccine exists.
I envision the situation, however, where it comes time for me to have a hip (or knee) replaced because the pain is just too unbearable, and the surgeon tells me that they are required - under penalty of losing their licenses and having the practice shuttered - to give me a COVID shot before they can do the surgery. That's not much of a choice. I also expect the government, especially if Biden/HeelsUp are in charge, to make proof of receiving the vaccine a condition of being permitted to board a flight or even to receive gubmint benefits, from Social Security to student loans.