Downtown Pittsburgh has become dangerous too, particularly during or after an event. There was a shooting after the 4th of July fireworks and more recently, another shooting after a musical event. Gangbangers have apparently have decided it's cool to move their shooting wars from the ghetto to downtown.
I used to work downtown, but lately, I try to avoid it at all costs, even during the day. It's sad because the city has undergone extensive renovation. Former office buildings are now hotels or condos/apartments. The mayor has been pushing suburbanites to move downtown and many have. But after all the recent violence, a number of those residents want out.