Something few realize is Germany and Italy only became unified countries in the late 1800s.
Historically regions like Bavaria were self-governing. So for example if they broke away from Germany proper, it would be reverting to the norm, not the opposite.
Likewise Sicily was a nation-state for centuries. And in the north of Italy the provinces were part of Austria.
Anyway Catalonia is carrying the water, for the independence movement for awhile.
I lived for awhile in Baden-Wurttemberg, an historic, prosperous, scenic region in Southern Germany. If Bavaria broke away, there goes BMW. If Baden-Wurttemberg breaks away, there goes Mercedes and Porsche, Audi.
Anyway local customs in Baden-Wurttemberg differed from the North. And remains so today. No shopping from 2 pm Saturday, until Monday morning. No washing cars on Sundays. Seems like not very much, but carefully guarded customs with religious roots.