This is what was brought up in the editorial section, the new pot laws, a lot of people see that as sinful.
Did God destroy cities over it? Seems some argue that all sin is an abomination in God's eyes.
Romans 6:23
And I wouldn't quote the Old Testament of God destroying cities unless one is talking from a Jewish point of view.
James 2:10-11 [Open in Logos Bible Software (if available)] says:
For whoever keeps the whole law but fails in one point has become accountable for all of it. {11} For he who said, “Do not commit adultery,” also said, “Do not murder.” If you do not commit adultery but do murder, you have become a transgressor of the law.
IOW, if you commit one sin, you are accountable for all sins.