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New Drug Clears Abnormal Brain Proteins Tied to Alzheimer's
http://www.livescience.com/55951-aducanumab-removes-alzheimers-plaques.htmlAugust 31, 2016
In people with Alzheimer's disease, a new investigational drug can dramatically reduce the amount of amyloid beta plaque, the tangled clumps of proteins that form in the brains of Alzheimer's patients, according to a new early study of the drug.
The drug works by spurring the immune system to recognize and clear the plaques.
"We believe that's a hint of efficacy," study co-author Dr. Alfred Sandrock, a neurologist and an executive vice president at Biogen, said during a news briefing. "We believe that needs to be confirmed with further studies." Biogen is the Cambridge, Massachusetts, company that funded the trial and applied to patent the drug.
However, the study was too small to show whether there was an effect on the patients' symptoms of Alzheimer's disease. And the drug can also cause fluid accumulations in the brain in some genetically susceptible people, the researchers reported today (Aug. 31) in the journal Nature....