December 22, 2025
Deaths of Despair: When the Soul of a Nation Grows Sick
By Brian C. Joondeph, M.D.
America’s “deaths of despair” - fatalities from drug overdoses, alcohol abuse, and suicide - have climbed for more than two decades, reaching levels unseen in modern times.
The long-run trend is stark. After mid-century stability, the curve bends sharply upward after 2000, driven first by drugs and later joined by alcohol and suicide. The data, drawn from the Senate Joint Economic Committee’s “Long-Term Trends in Deaths of Despair” report shown below, are clear. The deeper question is why.
COVID made a bad situation worse. Lockdowns and restrictions stripped away social contact, church gatherings, family support, and purpose. Economic uncertainty due to rising inflation, erratic labor markets, and a government staggering under debt has pushed people further into anxiety.
During 2020 and 2021, overdoses and alcohol-related deaths surged, while depression and loneliness became near-universal.
https://www.americanthinker.com/articles/2025/12/deaths_of_despair_when_the_soul_of_a_nation_grows_sick.html