Major Medical Mystery: Why Some People Despite Exposure Don’t Get COVID
by Dr. Joel S. Hirschhorn May 13, 2022
A global medical mystery is being aggressively pursued by medical researchers. The core issue is that a relatively small fraction of people despite high exposure to COVID have not gotten ill with COVID infection. Think of health workers in hospitals in contact with many seriously ill COVID patients. Also, members of households that stood out because unlike others in the home who got ill with COVID they did not get infected. The mystery is what explains how highly exposed individuals did not get ill with COVID infection.
There are two main ways of explaining resistance to COVID. One is that some people have strengthened their immune systems by any of a number of actions taken before or during the pandemic. For example, some may have elevated levels of vitamin D in their blood by taking high doses of supplements. The other explanation that appeals to medical researchers is that some people have a genetic makeup that gives them total defense against COVID infection.
It is necessary to eliminate people who got infected but were asymptomatic and also those who practiced many safe behaviors to avoid COVID exposure. The group that merits investigation are people who were definitely highly exposed to COVID but escaped infection.
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