What is Ibuprofen?
By Dr Liji Thomas, MD
Ibuprofen is a non-steroidal anti-inflammatory drug, or NSAID. It is a propionic acid derivative, and was the first in this group to be introduced. It is popular as an OTC analgesic-antipyretic drug, and is used in both children and adults.
Mechanism of action
Ibuprofen is a non-selective inhibitor of the cyclo-oxygenase (COX 1 and 2) enzymes, which are involved in prostaglandin synthesis. It reduces fever, inflammation and pain by its action on this pathway which plays an important role in inducing inflammation.
It is officially classified under the categories of analgesic, antirheumatic, musculoskeletal agent, and anti-migraine agent.
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