She might be the first candidate to cry at a POTUS debate. I hope Trump or DeSantis doesn't hold back.
My guess is that DeSantis will say very little negative about her, or really about any of the other candidates because he doesn't have to. You know Trump is going to go after everyone else hard, and DeSantis can just sit back knowing that Trump is taking out both those other candidates and himself at the same time. We're seeing that strategy in effect right now where he just doesn't respond directly to anything Trump says about him.
I'd imagine he will have a few lines prepped for when Trump goes off on him, but they'll be more subtle, like "Donald and I see many of the same problems that need fixing, but we just have different opinions about how we should go about communicating that to the American people", or "Maybe Donald and I are just from different generations, but I don't think his way is always the best to convince people to join your cause." A dig at the age factor without directly trashing Trump himself.