Regardless of differing opinions about Pence and what he did or should have done I think it's safe to say his political career is over.
I do agree with that. There are too many among rank-and-file Rs who feel that he failed on January 6 for him to ever overcome.
My arguments here are not intended as any kind of defense of him as a standard bearer; he strikes me as a milquetoast, not the assertive leader we need for a Conservative movement or for the United States. When he endorsed Cruz during the 2016 Indiana primary he was clearly afraid of how Trump and Trump's followers would react.
I don't consider him corrupt or dishonest, and I certainly don't blame him for his position on January 6, but I have never understood why Trump picked him, unless it was to cement ties with social conservatives. If he has any sense he will recognize reality and stop accepting speaking engagements at political events for a few years.