The Briefing Room
General Category => Health/Education => Topic started by: PeteS in CA on September 09, 2021, 09:26:04 pm
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Development study reveals origins of inflammatory bowel disease
https://medicalxpress.com/news/2021-09-reveals-inflammatory-bowel-disease.html (https://medicalxpress.com/news/2021-09-reveals-inflammatory-bowel-disease.html)
Many diseases have their origin in early human development, and today (8 September), two publications in Nature reveal how researchers from the Human Cell Atlas (HCA) consortium are advancing understanding of this. The global HCA initiative is mapping every cell type in the human body, to transform our knowledge of biology, infection and disease.
A new large-scale study mapped the cells in the human gut from early development through to adulthood, creating the most comprehensive cell atlas of the gut to date. This revealed that Crohn's disease may be caused by activation of developmental pathways, and uncovered potential drug targets for treating Crohn's and other inflammatory bowel diseases. The detailed maps will help explain how the gut forms and functions, and will transform research into intestinal diseases.