No, it's not "understandable." Biden's frustration with people who have come to different conclusions regarding the advisability of this novel vaccine is part and parcel with Hitler's expressed frustration with Europe and the Jews.
And, just like Hitler vis-a-vis the Jews, Biden is now engaged in the process of vilifying the unvaccinated and turning them into the hated "Other" whom it is acceptable - indeed it is required - to abuse.