From Macon County (Missouri) Health Dept.:
I don't know what Pepcid does for you. Whatever its benefit, I wonder if Prilosec would work as well.
Interesting. Dr Kauffman has repackaged the Zelenko regimen with some old-school patient care.
Quercetin: Zinc ionophore, an OTC substitute for HCQ or Ivermectin--. (5 day duration)
Zinc supplementation These two are key to inhibiting viral replication.(also 5 day duration).
Pepcid:... contains famotadine, a H2 Histamine blocker useful in stopping heartburn, but also has shown promise in preventing Cytokine Responses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673069/pdf/11_2020_Article_1422.pdf which are considered to be one of the real killers in late stage COVID. (The immune system runs amok, attacking healthy cells, accounting for diffuse blood clots in the lungs noted in many victims). In Zelenko's regimen, the macrolide antibiotics had that effect, even though it is idiopathic, of keeping the immune system from running wild and destroying healthy cells. The antibiotics also guarded against opportunistic infections, which pepcid, unfortunately, will not do. (While the paper cited is nearly a year old and assumes zoonotic origins as opposed to lab creation, that tidbit is irrelevant here: the important part is the effects of the pathogen and mitigation thereof.)
@mountaineer No, Prilosec works differently (proton pump inhibitor), and would not have the same effect as Pepcid (H2 histamine blocker). If you suffer from non-erosive GERD (without an
Heliobacter pylori infection) Prilosec has been shown to be superior for that condition.
https://pubmed.ncbi.nlm.nih.gov/15943841/ In this case, however, the strategy is to keep the immune system from running amok, ("Cytokine Storm"), which can be lethal, and the Pepcid is the medication which will accomplish that best of the two.
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Next part:
Getting the crud out:
Mucinex: to loosen phlegm and keep the lungs clear (some coughing required to remove the secretions).
"Tummy time": This used to be called "postural drainage", using body position to help move mucous out of the deeper reaches of the lungs into the bronchioles where it can be expelled. By changing position (back, side, stomach, other side), and even adopting a slight head down posture, that drainage of pulmonary secretions is enhanced, and gravity works for you.
Deep breathing and walking. Deep breathing opens the lungs, and will help keep secretions from pooling. Yep, there will be coughing involved. Don't suppress that, you want to get that gunk out. Walking will increase the need for oxygen, which will get your body to breathe deeper, and to push more phlegm out of your lungs, and also has the effect of reducing the likelihood of a DVT (blood clots in the legs from inactivity).
Not only is phlegm removal essential to pulmonary function, the more dead cells and mucous you cough out, the less the body has to clean up, and the absence of pools of mucous in your lungs reduces the availability of micro environments for opportunistic bacterial infections to take hold in your respiratory system.
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ASA: acetylsalicylic acid (aspirin), "low dose". Ordinary dosages of aspirin are 325mg, this is the low dose intended to prevent clotting, especially DVT (deep vein thrombosis), which walking will also help to prevent.
Omega-3 supplement: also has effects on the immune system, but in concert with Vitamin C reduces bronchoconstriction in athletes (and others) with asthma.
https://clinicaltrials.gov/ct2/bye/rQoPWwoRrXS9-i-wudNgpQDxudhWudNzlXNiZip9Ei7ym67VZRCnxR4VFR0VA6h9Ei4L3BUgWwNG0it. and
https://pubmed.ncbi.nlm.nih.gov/17412579/ Omega-3 supplementation has shown a wide variety of positive effects, especially in an aging population.
B vitamins: Energy. In a nutshell.
Potassium rich foods:
There has been observed hypokalemia (low potassium levels) in COVID patients, and this electrolyte imbalance can have severe results.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781399/ (some interesting links in the references for further reading)
Potassium rich foods will help prevent those low levels which especially would adversely affect heart function.
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Additional commentary:
In a word, BRILLIANT! Kudos to Dr Kauffman!
With common supplements and no need whatsoever for prescription medication, this covers every strategic function in the Zelenko regimen with the addition of some old-school methodology for congestion control and the antibacterial effects of the macrolide antibiotics. (Postural drainage was one of the things used against pneumonia in the days before antibiotics, to help clear the lungs--{Yes, I read old medical texts from pre-WWII, because with antibiotic resistance growing, or in the event they were not available, we might be back to that.}
Since then, we have become reliant on the magic bullet--absent in viral diseases, as a rule--to kill off the infection, and in clinical settings patients are commonly only elevated or lowered while maintaining a dorsal down posture, which may be less beneficial to the patient for the purposes of expelling accumulating mucous loads in the lungs than being able to lay on their sides and stomach for short periods to help drain mucous from the lungs.)
