In Mexico deaths were 50% higher for 8 months, then it starts Ivermectin…

[Elderberry]

JoNova 7/5/2021

For a whole year more people were dying in Mexico than normally died. There’s been one long bloodbath there and an untold story. Mexico may not have hit the “photogenic” headline stage that Brazil, Iran, and India did, but nonetheless, somewhat unnoticed, it’s been continuously bad. Mexico has the dubious honor of being one of the worst for testing, with positivity rates at the virtually the highest in the world, running at 35% and even reaching over 50% at times. Few countries have had higher rates (currently only Tunisia, Namibia, maybe Colombia are worse).  The Case Fatality Rate has run at 12% for a year, only confirming that there weren’t enough tests to know the real scale of the infections.  The excess deaths graph tells its own story. The wave of 2020 ran for a whole year with deaths running at 50 – 100% higher than in a normal year. Since the pandemic began some 350,000 excess deaths have been recorded. The death toll for Covid in Mexico may be 60% higher than the official Covid casualty count of 230,000.  As winter made the situation even worse, things got desperate enough (finally!) for cheap treatments to be organized.

Ivermectin use at 200 microgram/kg started on December 21 and was gradually rolled out across Mexico. It took months, but finally, for the first time in a year, Mexican deaths are back to normal, and even slightly lower.

Obviously some countries are too rich to use cheap drugs. For them, only patentable ones with big profits attached can “solve” this crisis.

Vaccinations did not start en masse til February 15th, and by the start of June only 17% of the country had even received one dose.



How many lives would have been saved and how many lockdowns could have been prevented?

Obviously excess deaths in a pandemic are also due to hospitals being overwhelmed, and shortages or restrictions and the failure of normal healthcare. It may be years before those factors can be unravelled and a better estimate of Covid deaths can be made.

After Mexico City introduced Ivermectin, COVID hospitalizations and deaths were reduced

More: https://joannenova.com.au/2021/07/mexico-uses-ivermectin/

[Hoodat]

There is a special place in hell for media pundits and other Democrats who misled the people on anti-parasitic drugs resulting in the avoidable deaths of tens of thousands of Americans.

[PeteS in CA]

In real life, this, https://www.worldometers.info/coronavirus/country/mexico/ , shows that Mexico had a massive surge in daily new cases in December-January, just like the US and many other countries. Their new cases numbers in February-May did not plummet as precipitously or to the degree that new cases did in the US. Unlike the US, Mexico started a new surge of new cases in early June that may still be increasing. Sadly, daily deaths have also surged in June.

I don't know who Joanne Nova is or her views on Covid treatment and prevention, but her claim regarding Covid in Mexico is not true. AFAIK, Ivermectin does hinder infections when used properly, but it's no Magic Kovid-Killing Silver Bullet.

[catfish1957]

Have been giving our pups Ivermectin for heart worm prevention for 25 years.  OTOH, there has been some data showing this drug can lead to seizures.  And our last English Bulldog died from one, where he went into a coma, and did not come out.

Arbitrarily suggesting or recommending its use for COVID treatment without study is irresponsible. 

[Elderberry]

Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

https://journals.lww.com/americantherapeutics/Fulltext/2021/06000/Review_of_the_Emerging_Evidence_Demonstrating_the.4.aspx
 
American Journal of Therapeutics: May/June 2021 - Volume 28 - Issue 3 - p e299-e318 by Kory, Pierre MD1,*; Meduri, Gianfranco Umberto MD2; Varon, Joseph MD3; Iglesias, Jose DO4; Marik, Paul E. MD5

Abstract

Background:

After COVID-19 emerged on U.S shores, providers began reviewing the emerging basic science, translational, and clinical data to identify potentially effective treatment options. In addition, a multitude of both novel and repurposed therapeutic agents were used empirically and studied within clinical trials.

Areas of Uncertainty:

The majority of trialed agents have failed to provide reproducible, definitive proof of efficacy in reducing the mortality of COVID-19 with the exception of corticosteroids in moderate to severe disease. Recently, evidence has emerged that the oral antiparasitic agent ivermectin exhibits numerous antiviral and anti-inflammatory mechanisms with trial results reporting significant outcome benefits. Given some have not passed peer review, several expert groups including Unitaid/World Health Organization have undertaken a systematic global effort to contact all active trial investigators to rapidly gather the data needed to grade and perform meta-analyses.

Data Sources:

Data were sourced from published peer-reviewed studies, manuscripts posted to preprint servers, expert meta-analyses, and numerous epidemiological analyses of regions with ivermectin distribution campaigns.

Therapeutic Advances:

A large majority of randomized and observational controlled trials of ivermectin are reporting repeated, large magnitude improvements in clinical outcomes. Numerous prophylaxis trials demonstrate that regular ivermectin use leads to large reductions in transmission. Multiple, large “natural experiments” occurred in regions that initiated “ivermectin distribution” campaigns followed by tight, reproducible, temporally associated decreases in case counts and case fatality rates compared with nearby regions without such campaigns.

Conclusions:

Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified.

DISCUSSION

In summary, based on the totality of the trials and epidemiologic evidence presented in this review along with the preliminary findings of the Unitaid/WHO meta-analysis of treatment RCTs and the guideline recommendation from the international BIRD conference, ivermectin should be globally and systematically deployed in the prevention and treatment of COVID-19.

[Elderberry]

COVID-19 Long-Haulers Turning to Ivermectin for Relief, But Questions Over Drug’s Effectiveness Linger

WTTW by Kristen Thometz | July 2, 2021

https://news.wttw.com/2021/07/02/covid-19-long-haulers-turning-ivermectin-relief-questions-over-drugs-effectiveness

Streeterville resident Valerio Cerron led an active lifestyle before testing positive for COVID-19 in late February.

Before the pandemic, the 35-year-old ran up to 5 miles daily, had a busy social life and traveled regularly for work.

While his coronavirus infection was mild, his symptoms lingered beyond the expected two to three weeks. “I was still experiencing shortness of breath symptoms, chest pain,” he said, adding that even long conversations took a toll. “Sometimes I have to catch my breath a lot. … It’s a disconcerting feeling because you expect you’re going to get better like everybody else.”

Patrick McBriarty can relate. The 56-year-old author who lives in North Center used to be an avid cyclist, biking around 2,000-3,000 miles per year. But that changed when he contracted COVID-19 in March 2020. His case was also mild, but he has experienced symptoms for more than a year.

McBriarty and Cerron are among those known as long-haulers, people whose COVID-19 symptoms linger well beyond their initial infections. In their quests to get better, they have each tried numerous remedies, including an antiparasitic medicine used to treat tropical diseases and scabies called ivermectin.

Some doctors say it’s time for the drug to get a green light.

“Ivermectin is one of the safest drugs known in history,” said Dr. Pierre Kory, a pulmonary and critical care specialist based in Wisconsin, who notes that the scientists who discovered the compound that led to the drug’s development received the Nobel Prize.

Testifying before the U.S. Senate in December, Kory advocated for the use of ivermectin for COVID-19 on behalf of the Front Line COVID-19 Critical Care Alliance, an international group of physicians and scientists that believes ivermectin is a “miracle drug” for COVID-19 and should be used immediately.

“There’s a lot of controversy as agencies say they need more data because that’s what they always do,” said Kory, who’s the president and chief medical officer of the alliance. “There’s been lots of successes, lots of doctors are using it and saying it’s really effective.”

The alliance has developed protocols for using the drug to prevent and treat COVID-19, including guidelines specific to long-haulers.: I-RECOVER Management Protocol for Long Haul COVID-19 Syndrome (LHCS)

[Hoodat]

Ivermectin does hinder infections when used properly, but it's no Magic Kovid-Killing Silver Bullet.

No one is suggesting that it is.  It simply increases the chance of survival for those infected.

[PeteS in CA]

No one is suggesting that it is.  It simply increases the chance of survival for those infected.

https://www.gopbriefingroom.com/index.php/topic,440313.0.html

https://www.gopbriefingroom.com/index.php/topic,438660.0.html

[Hoodat]

https://www.gopbriefingroom.com/index.php/topic,440313.0.html

https://www.gopbriefingroom.com/index.php/topic,438660.0.html

In both links, ivermectin saved lives.  Not sure I would call it a silver bullet by reading those links though.

[libertybele]

In both links, ivermectin saved lives.  Not sure I would call it a silver bullet by reading those links though.

No, and I get that it's not a silver bullet, but it has saved lives.  So in that aspect, what's the downside? 

Cost?  I'd venture to say it is far less expensive to manufacture than the current vaccines and Ivermectin has been around much longer and as far as I know, not many have died from using it as opposed to thousands who have died from the current vaccines.

[Elderberry]

No, and I get that it's not a silver bullet, but it has saved lives.  So in that aspect, what's the downside? 

Cost?  I'd venture to say it is far less expensive to manufacture than the current vaccines and Ivermectin has been around much longer and as far as I know, not many have died from using it as opposed to thousands who have died from the current vaccines.

You nailed it on cost. The doctors won't get as much kickback.