Author Topic: Map of malaria parasite's gene activity reveals new targets for drugs, vaccines  (Read 245 times)

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Offline PeteS in CA

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Map of malaria parasite's gene activity reveals new targets for drugs, vaccines

https://www.upi.com/Science_News/2021/05/27/britain-malaria-parasite-gene-activity-maps/3701622061862/

Quote
May 27 (UPI) -- New cellular maps of the malaria parasite have revealed the genetic transformations Plasmodium falciparum undergoes before infection.

The atlas, published Thursday in the journal Nature Communications, has already identified several potential targets for future drugs and vaccines.

Over the last 20 years, malaria-carrying mosquitoes have become increasingly resistant to pesticides, while the parasite itself has become increasingly unfazed by antimalarial drugs.
...
To identify potential new drug and vaccine candidates for malaria infections, researchers analyzed the gene activity associated with the parasite's different development stages.

Scientists isolated the parasite at different lifecycle stages and produced nearly 1,500 transcriptomes, maps of which genes are turned on and off at any given moment.
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Knowing which genes orchestrate this process -- and how -- can help scientists design drugs to disrupt the parasite's lifecycle and thwart infection.

One of the quiet health crises worldwide is how the malaria parasite has developed resistance to existing drugs, with some regions of the world having their own unique single remaining effective antimalarial drug. A person travelling to some parts of the world have to research what drug is useful where they'll be travelling and possibly being only able to purchase it at their destination.

So this research could lead to game-changing developments, both in prevention and in eradicating the parasite from the systems of people who have had the disease and are subject to occasional unpredictable recurrences.
If, as anti-Covid-vaxxers claim, https://www.poynter.org/fact-checking/2021/robert-f-kennedy-jr-said-the-covid-19-vaccine-is-the-deadliest-vaccine-ever-made-thats-not-true/ , https://gospelnewsnetwork.org/2021/11/23/covid-shots-are-the-deadliest-vaccines-in-medical-history/ , The Vaccine is deadly, where in the US have Pfizer and Moderna hidden the millions of bodies of those who died of "vaccine injury"? Is reality a Big Pharma Shill?

Millions now living should have died. Anti-Covid-Vaxxer ghouls hardest hit.