I'm a life-long civilian, so maybe I'm wrong, but being the first to see/detect the enemy seems a rather important factor. So a difficult to detect fighter like an F-22 or F-35 seems likely to have a significant advantage over any Gen 4 or earlier opponent.
X vs. Y one-on-one hypothetical evaluations that assume both identify each other simultaneously are usually not very realistic.
Think volume.... our 24 aircraft against 40 of theirs, not just one on one...
You race into battle, take your shots and RTB to rearm, reload and relauch... You may take damage from ground fire or SAMS, or the plane just breaks under the stresses, so now you only have 23 aircraft.
Can you repair the plane and get it ready for war again in a short amount of time?
We would have to pull tree branches out of the wheel wells on the F-4's they were flying so low but they still flew.
The F-4 would come back with many bullet holes and would still fly.... can the new glitter birds do that?
Too much reliance on technology blinds to many to reality.