What is Marfan Syndrome?
By Afsaneh Khetrapal, BSc (Hons)
Marfan syndrome occurs in approximately 1 in every 5000 individuals. It is an autosomal dominant disorder therefore the majority of people with Marfan syndrome have a 50% chance of inheriting the defective gene from whichever parent who suffers from the disorder. Alternatively, in approximately 25-30% of those with Marfan syndrome the condition has developed due to a spontaneous mutation yielding the defective gene.
Marfan syndrome affects the body’s connective tissues – these are required for the body to maintain its structure and provide necessary structural support to other tissues and organs. Connective tissue is usually strong and resilient – it is made up of a number of proteins which include collagen, elastin and fibrillin.
https://www.news-medical.net/health/What-is-Marfan-Syndrome.aspx
