Do we want to empower the state to monitor and test each and every citizen of the country to ensure that they are following prescription protocols?
Maybe empower the state to simply ban and restrict all opioids from dispense to the public? Require all citizens to keep their medicines at their doctor's office and make them go there to receive them?
Empower government to require extra insurance and limits upon what kind of medicine bureaucrats say you are permitted to have, if any?
If we as a people want safety and security above all else, - then we do not want liberty. We want Government to be our god and our nanny.
Which is how despotic meddlesome tyrannies are established.
Yes, this is the problem. A couple of cases to consider, that are already an issue:
1) People who have TB, who have to take meds on a schedule to avoid infecting others. Right now, healthcare people are having to go their houses daily to watch them take their meds. It's a form of quarantine, I suppose. But they are trying to mandate compliance with the TB regimen.
2) People who have various mental illnesses who are functional when on their meds but become delusional and dangerous when off them. Different programs work to monitor their compliance.
I don't see a way around this enforced medication with regard to specific diseases. Maybe the guideline would be something that necessitates a quarantine. Rather than locking someone in their house or an institution for the rest of their lives, by complying with their medication regime they could function in society.
But these diseases, both mental and physiological, DO EXIST. And with antiobiotic-resistant infections coming up, they're not going away.
Simply saying we can't let the government control this, is burying our heads in the sand.