Sure, but you will need mid-course corrections in all likelihood.
It all depends on how 'surgical' you want the strike to be. If you have enough rock, say an anticipated radius of destruction 2 times the diameter of the intended target area or more, your success is more likely than just throwing something intending to take out a smaller area. in a situation where 'surgical' might mean the elimination of a major metro area, a little slop might get an extra country or two (thinking Europe or Africa, for instance). In larger countries an extra state or province. If you want precision, I'd think it would take something smaller, likely manufactured rather than cut loose as a chunk, and that can be maneuvered, both inbound, and possibly in atmosphere. (The 'Rods from god' approach to kinetic apocalypse.)