The Tsar Bomba weighed in at 30 tons. With modern materials, maybe you could get a 100 MT blast with the same weight. That is about the limit of what the Falcon Heavy could put in orbit, maybe a little less. You'd need at least two launches of a FH, one for the bomb, and another for the escape stage. The senate launch system, if it ever gets going, could probably do it, though just barely.