Pulling the String on Yo-Yo Weight Gain
Mice that lost weight and then gained back more than they lost maintained an obesity-type microbiome that affected biochemicals involved in either burning or adding fat--suggesting interventions.
“We focus on what is called recurrent obesity or yo-yo obesity, which is a feature which affects close to 80 percent of all overweight individuals worldwide.”
Eran Elinav of the Weitzmann Institute of Science in Israel.
https://www.scientificamerican.com/podcast/episode/pulling-the-string-on-yo-yo-weight-gain/