New Alzheimer’s drug is huge leap forward for sufferers: Slows Cognitive Decline or Even Halts It

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SOURCE: THE TIMES

URL: http://www.thetimes.co.uk/edition/news/alzheimers-drug-is-huge-leap-forward-for-sufferers-dkmbnncbm

by: JONATHAN BRADY


The first powerful treatment for Alzheimer’s is on the horizon after a new drug was found to combat the changes to the brain that cause the disease.

Scientists hailed the breakthrough as the best news in dementia research for a quarter of a century and others said that it could be a “game changer”.

British people in the early stages of the condition are being signed up for a large-scale clinical trial of the monthly injection, which appears to break up the poisonous lumps that form in the brains of sufferers. The drug can also slow cognitive decline or even halts it altogether, the evidence suggest.

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More info:

New Drug Clears Abnormal Brain Proteins Tied to Alzheimer's
http://www.livescience.com/55951-aducanumab-removes-alzheimers-plaques.html
August 31, 2016

In people with Alzheimer's disease, a new investigational drug can dramatically reduce the amount of amyloid beta plaque, the tangled clumps of proteins that form in the brains of Alzheimer's patients, according to a new early study of the drug.

The drug works by spurring the immune system to recognize and clear the plaques.

"We believe that's a hint of efficacy," study co-author Dr. Alfred Sandrock, a neurologist and an executive vice president at Biogen, said during a news briefing. "We believe that needs to be confirmed with further studies." Biogen is the Cambridge, Massachusetts, company that funded the trial and applied to patent the drug.

However, the study was too small to show whether there was an effect on the patients' symptoms of Alzheimer's disease. And the drug can also cause fluid accumulations in the brain in some genetically susceptible people, the researchers reported today (Aug. 31) in the journal Nature....