And here is what we are fighting, in a nutshell. It's a hydra. Cut off the head and two new ones grow. The explosion / assassination happened yesterday evening. This afternoon, a new command structure is in place and they'll carry on as normal. Maybe slightly less effectively, but I'd not count on it.
There is only three ways to kill a hydra.
Choke it to death - cut off it's funding and supply routes.
Start at the tail and work up - target the low level grunts first.
Poison it before it breeds - a legitimate use of the phrase "hearts and minds."
Ahrar al-Sham is not the force it once was, but the same techniques apply to ISIL and AQ.