The Briefing Room

General Category => Health/Education => Topic started by: endicom on August 07, 2018, 12:54:33 am

Title: Stem cell treatment of Parkinson’s disease via half inch holes in the skull
Post by: endicom on August 07, 2018, 12:54:33 am
Next Big Future
Brian Wang
Aug. 6, 2018

Kyoto University Hospital will start clinical trials for Parkinson’s disease that transplants dopaminergic progenitors generated from induced pluripotent stem (iPS) cells.

About 5 million iPS cell-derived dopaminergic progenitors will be transplanted by stereotaxic brain surgery into the left and right sides of the patient’s putamen.

More... https://www.nextbigfuture.com/2018/08/stem-cell-treatment-of-parkinsons-disease-via-half-inch-holes-in-the-skull.html (https://www.nextbigfuture.com/2018/08/stem-cell-treatment-of-parkinsons-disease-via-half-inch-holes-in-the-skull.html)
Title: Re: Stem cell treatment of Parkinson’s disease via half inch holes in the skull
Post by: Suppressed on August 08, 2018, 06:18:41 am
Quote
into the left and right sides of the patient’s putamen

Holy moley, that's not just on the surface! 

IIRC, the putamen is thought to be linked to feelings of hatred.  I hope this procedure doesn't act as a trigger, but is instead a successful therapy.
Title: Re: Stem cell treatment of Parkinson’s disease via half inch holes in the skull
Post by: GtHawk on August 09, 2018, 03:31:13 am
Holy moley, that's not just on the surface! 

IIRC, the puts men is thought to be linked to feelings of hatred.  I hope this procedure doesn't act as a trigger, but is instead a successful therapy.
https://www.ncbi.nlm.nih.gov/pubmed/28585051

Abstract
The putamen is a subcortical structure that forms part of the dorsal striatum of basal ganglia, and has traditionally been associated with reinforcement learning and motor control, including speech articulation.
Title: Re: Stem cell treatment of Parkinson’s disease via half inch holes in the skull
Post by: Suppressed on August 12, 2018, 11:03:03 pm
https://www.ncbi.nlm.nih.gov/pubmed/28585051

Abstract
The putamen is a subcortical structure that forms part of the dorsal striatum of basal ganglia, and has traditionally been associated with reinforcement learning and motor control, including speech articulation.


DAILY NEWS  28 October 2008
‘Hate circuit’ discovered in brain
https://www.newscientist.com/article/dn15060-hate-circuit-discovered-in-brain/ (https://www.newscientist.com/article/dn15060-hate-circuit-discovered-in-brain/)

[...]

The results showed two brain regions that our “hate circuit” shares with the “love circuit” – the putamen and the insular cortex or insula.

The putamen is thought to be used to prepare the body for movement – so it’s possible this be active either to provide protection of the loved one, or to prepare for an aggressive or spiteful act from the hated one. The insula is associated with feelings of distress, such as jealousy.

Scheming hatred
However, there was also an important difference. The areas of the frontal cortex associated with judgement and reasoning are typically less active when viewing a lover compared to someone more neutral, meaning they are less likely to feel critical of their partner.

The hate-filled subjects, though, only showed a reduction in one small part of this area, while the rest was still active.

[...]