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Unlucky 10% have gene that makes it difficult to digest caffeine 10% of the population at a greater risk of heart attacks when they drink coffee James Madison University, Virginia, tested 101 male athletes in their latest study They found the gene CYPIA2 determines how we process caffeine in our bodies Meanwhile 50 per cent of us have a CYPIA2 gene that digests caffeine normallyBy Jack Flanagan For MailonlinePublished: 05:05 EDT, 29 March 2018 | Updated: 06:56 EDT, 29 March 2018It's long been used by athletes as a legal stimulant to boost their performance.But a new study claims caffeine has the wrong effect on an unlucky 10 per cent of people when they exercise - making them run slower.A trial on student athletes discovered the majority ran 6km (3.7 miles) quicker after drinking it - but a handful were 14 per cent slower.Read more at: http://www.dailymail.co.uk/health/article-5557561/Unlucky-10-gene-makes-difficult-digest-caffeine.html